Table of Contents
What is an example of tetrasomy?
Examples of tetrasomy are as follows: tetrasomy 9p. tetrasomy 18p. tetrasomy 12p (Pallister-Killian syndrome)
What is the effect of tetrasomy?
Tetrasomy 18p is a chromosomal condition that affects many parts of the body. This condition usually causes feeding difficulties in infancy, delayed development, intellectual disability that is often mild to moderate but can be severe, changes in muscle tone, distinctive facial features, and other birth defects.
Where does tetrasomy mutation occur?
Chromosome 18, Tetrasomy 18p is a rare chromosomal disorder in which the short arm of chromosome 18 (18p) appears four times (tetrasomy) rather than twice in cells of the body. Chromosomes are found in the nucleus of all body cells. They carry the genetic characteristics of each individual.
What is the difference between trisomy and tetrasomy?
Trisomy – the gain of an extra copy of a chromosome; individuals are called trisomics and their chromosomal composition is 2N+1. Tetrasomic – the gain of an extra pair of homologous chromosomes; individuals are called tetrasomics and their chromosomal composition is 2N+2.
Can you produce a baby with 48 chromosomes?
However, because of nondisjunction, an egg cell or a sperm cell can also end up with two extra copies of the X chromosome. If an egg cell with two extra X chromosomes (XXX) is fertilized by a sperm cell with one Y chromosome, the resulting child will have 48,XXXY syndrome.
What are other chromosomal abnormalities that can occur?
Some chromosomal abnormalities occur when there is an extra chromosome, while others occur when a section of a chromosome is deleted or duplicated. Examples of chromosomal abnormalities include Down syndrome, Trisomy 18, Trisomy 13, Klinefelter syndrome, XYY syndrome, Turner syndrome and triple X syndrome.
What are the symptoms of chromosome 18 tetrasomy 18p?
Chromosome 18, Tetrasomy 18p is a very rare chromosomal disorder in which the short arm of chromosome 18 (18p) appears four times (tetrasomy) rather than twice in cells of the body. Symptoms may vary from case to case. Many infants with Chromosome 18, Tetrasomy 18p have a low birthweight, feeding problems, and a tendency to vomit.
What causes tetrasomy X and what are the symptoms?
Tetrasomy X is caused by a random error that occurs during the development of an egg cell and is not caused by anything a mother does during her pregnancy. [1] [2] This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person.
What happens to the brain with tetrasomy 18p?
In addition, in some individuals with Tetrasomy 18p, electrical disturbances may occur in the brain, causing involuntary tightening and relaxing (clonus) of specific muscles or muscle groups (motor seizures). Many individuals with Chromosome 18, Tetrasomy 18p may also exhibit kidney (renal) abnormalities.
How many cases of tetrasomy 9p are there?
Chromosome 9, Tetrasomy 9p is a very rare chromosomal disorder that appears to affect males slightly more often than females. Approximately 30 cases have been reported in the medical literature.