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How do you test for HTLV?

Posted on May 16, 2020 by Sherryl Cole

How do you test for HTLV?

Typically, an EIA (enzyme immunoassay) test method is used initially to detect HTLV-I and HTLV-II antibodies in the blood. If the initial test is positive, a second method, such as Western blot, is ordered to confirm the finding and to help distinguish between HTLV-I and HTLV-II.

What is HTLV positive?

Positive LIA results provide confirmatory evidence of infection with HTLV-I or HTLV-II. A reactive screening result with a negative or indeterminate confirmatory test result suggests either a false-reactive screening test result or a seroconverting HTLV infection.

What are the symptoms of HTLV 2?

Symptoms

  • Sensory neuropathies (conditions that affect the nerves that provide feeling)
  • Gait abnormalities.
  • Bladder dysfunction.
  • Mild cognitive impairment.
  • Motor abnormalities (loss of or limited muscle control or movement, or limited mobility)
  • Erectile dysfunction.
  • Mycosis fungoides.

How to test for HTLV 1 and 2?

Values are valid only on day of printing. Qualitative screening detection of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/-2) specific antibodies with confirmation and differentiation between HTLV-1 and HTLV-2 infection

How to detect human T-cell lymphotropic virus 1?

Qualitative screening detection of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/-2) specific antibodies with confirmation and differentiation between HTLV-1 and HTLV-2 infection Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

When did HTLV screening begin in the United States?

Screening of the U.S. blood supply for HTLV-I/II, which began in 1988, identifies HTLV-I- and HTLV-II-infected persons who should be counseled regarding their infections.

How is HTLV-I transmitted by blood transfusion?

Transmission of HTLV-I by blood transfusion occurs with transfusion of cellular blood products (whole blood, red blood cells, and platelets) but not with the plasma fraction or plasma derivatives from HTLV-I-infected blood.

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