What are the protocol and precautions to be followed for blood storage?
Red blood cell components must be kept at a temperature of +2 °C to +10 °C during transportation. All components routinely stored at +20 °C to +24 °C should be kept at these temperatures during shipment. The transit time for blood and blood components should not normally exceed 24 hours.
What is SOP in blood bank?
To ensure safe blood, all the processes involved in blood collection up to transfusion to the patients require application of Standard Operating procedures (SOPs). SOPs that have been added here must be followed by each blood transfusion centres if the SOPs are matching with their requirement.
What agency issues guidelines standards for technical standards for blood banks?
Based on the principle of delivering quality health care services, the Blood Safety Program under the Department of Medical Services has developed a manual on “National Standards for Blood Transfusion Service” based on “Good Manufacturing Practices” (GMP) with objective to maintain and enhance the quality and safety of …
Which anticoagulant is used in blood bank?
Acid citrate dextrose
Acid citrate dextrose is the most commonly used anticoagulant to store blood in the blood banks as it prevents coagulation by inhibiting the action of the calcium ions.
What is the function of CPDA anticoagulant?
citrate phosphate dextrose adenine (CPDA-1) an anticoagulant solution, containing citric acid, sodium citrate, monobasic sodium phosphate, dextrose, and adenine, used for the preservation of whole blood and red blood cells for up to 35 days; it extends red cell survival by providing adenine needed for the maintenance …
In which organ the blood is stored?
Another useful purpose of your spleen is storing blood. The blood vessels in human spleens are able to get wider or narrower, depending on your body’s needs. When vessels are expanded, your spleen can actually hold up to a cup of reserve blood.
How is Plateletpheresis done?
Plateletpheresis is the standard procedure by which platelets are separated from whole blood, concentrated, and collected. To remove platelets, a needle is placed in each arm. Blood flows through a needle into a machine that contains a sterile, disposable plastic kit specifically designed for this purpose.
How does a blood bank work?
Blood bank: : A place where blood is collected from donors, typed, separated into components, stored, and prepared for transfusion to recipients. A blood bank may be a separate free-standing facility or part of a larger laboratory in a hospital.
What is the meaning of RA 7719?
Republic Act No. 7719, also known as the National Blood Services Act of 1994, promotes voluntary blood donation to provide sufficient supply of safe blood and to regulate blood banks. This act aims to inculcate public awareness that blood donation is a humanitarian act.
Is hypertension contraindication to blood transfusion?
Dr. Mosenthal writes that he has not advocated transfusions for high blood pressure. Furthermore, he believes that transfusions of blood in cases of essential hypertension would be contraindicated, as many of these patients have a tendency to a higher red blood cell count than the average normal person.
Which chemical is used to preserve blood?
The disodium calcium complex may be used for the preservation of whole blood. It is completely atoxic. Ethyl alcohol-saline-sugar solutions preserve erythrocytes for at least 150 days; they are excellent preservatives for the agglutinogens. Whole blood preserved with glycerin-raffinose-glucose may be frozen at —20° C.
What are the standards for a blood bank?
A-1.3 Blood bank should comply with laid-down standards in Drugs and Cosmetic Rules in recruitment and selection of blood donors, collection, processing, storage and distribution. A-2.0 All blood banks should have their own quality policy and prepare a quality manual that addresses the systems in use.
What should be included in the format of SOP?
Format of SOP The format of SOP must have all the information and instruction that covers the whole purpose of particular activities. It should include all the relevant information and directions to complete a laboratory process from starting to end including the step by step process,
Who is responsible for reporting deviations from protocol?
Sponsored research agreements may require the PI to notify the sponsor of all unplanned deviations or departures from IRB approved protocol procedures. Sponsor reporting requirements for deviations may differ from JHM IRB reporting requirements. It is the PI’s responsibility to comply with the reporting requirements outlined in the signed contract.
When to report protocol deviations in the eirb?
Reporting Protocol Deviations. The sponsor and the IRB of record must be notified as soon as possible, but not later than 5 days after the emergency situation occurred ( 21 CFR 812.150 (a) (4) )*. The PI must submit a report to the IRB of record in eIRB via a Further Study Action for Protocol Event Report.