Table of Contents
What happens if you take abiraterone with food?
Abiraterone acetate (trade named Zytiga) has a greater positive food effect–an increase in the amount absorbed when taken with food–than any other marketed drug that is labeled to be taken on an empty stomach.
How effective is abiraterone acetate?
The pooled analysis reported abiraterone acetate showed significant efficacy in high-risk prostate cancer patients, including overall survival (OS) [HR 0.66, 95% confidence interval (CI), 0.61–0.73, P<0.001], the time to prostate-specific antigen (PSA) progression (HR 0.45, 95% CI, 0.34–0.59, P<0.001), progression-free …
Is abiraterone acetate FDA approved?
On February 7, 2018, the Food and Drug Administration (FDA) approved abiraterone acetate (Zytiga, Janssen Biotech Inc.) tablets in combination with prednisone for metastatic high-risk castration-sensitive prostate cancer (CSPC).
Is abiraterone acetate chemotherapy?
by Drugs.com Zytiga (abiraterone acetate) is a type of hormone therapy that is used along with prednisone to treat men with prostate cancer that has spread to other parts of the body (metastasized). Despite being used to treat cancer, Zytiga is not a form of chemotherapy.
What happens when you stop Zytiga?
Stop taking Zytiga® and see a doctor immediately if you notice signs of low blood potassium: muscle weakness. muscle twitches. heart palpitations.
How successful is Zytiga?
Zytiga treated patients survived on average 53 months compared to 36.5 months for ADT alone. The combination of Zytig plus prednisone with can now be considered standard of care in patients with high-risk CSPC.
Does abiraterone affect the immune system?
Abiraterone doesn’t affect your immune system or involve regular hospital visits. For this reason, abiraterone may be safer for you than chemotherapy until the risk from coronavirus in the UK has reduced.
What are the side effects of Zytiga?
The most common side effects of ZYTIGA® include:
- Feeling very tired.
- Joint pain.
- High blood pressure.
- Nausea.
- Swelling in your legs or feet.
- Low blood potassium levels.
- Hot flushes.
- Diarrhea.
Who manufactures abiraterone acetate?
ZYTIGA (abiraterone acetate) was developed by Ortho Biotech Oncology Research & Development, a Unit of Cougar Biotechnology, Inc., and will be marketed by Centocor Ortho Biotech Inc.
How long can you survive Zytiga?
After a median follow-up of 51.8 months and a final analysis the overall survival has been confirmed to be significantly longer for patients receiving Zytiga/ADT/prednisone. Zytiga treated patients survived on average 53 months compared to 36.5 months for ADT alone.
How long can you stay on Zytiga?
Many people with prostate cancer take Zytiga for 2–3 years, so the costs associated with their treatment can run into hundreds of thousands.
What is the brand name for abiraterone acetate?
This use is approved for the Zytiga brand name of abiraterone acetate. Abiraterone is also being studied in the treatment of other types of cancer. Definition from the NCI Drug Dictionary – Detailed scientific definition and other names for this drug.
Is there an antidote for abiraterone acetate overdose?
Clinical experience with overdose of abiraterone acetate is limited. There is no specific antidote for abiraterone acetate overdose, and treatment should consist of general supportive measures, including monitoring of cardiac and liver function.
When to start abiraterone acetate for prostate cancer?
Newly diagnosed metastatic prostate cancer within 3 months prior to randomization with histologically or cytologically confirmed adenocarcinoma of the prostate without neuroendocrine differentiation or small cell histology
When to discontinue abiraterone acetate plus prednisone?
Participants will discontinue study treatment at disease progression or unacceptable toxicity unless, in the Investigator’s opinion, it is deemed that the participants will continue to derive benefit from study treatment.