Table of Contents
Can BCC spread to the eye?
The vast majority of skin cancers around the eyes are basal cell carcinomas (BCCs). While BCCs rarely spread to the lymph nodes or beyond, they can grow large enough to cause disfigurement around your eyes.
What is the action of fluorouracil?
The fluoropyrimidine 5-fluorouracil (5-FU) is an antimetabolite drug that is widely used for the treatment of cancer, particularly for colorectal cancer. 5-FU exerts its anticancer effects through inhibition of thymidylate synthase (TS) and incorporation of its metabolites into RNA and DNA.
How is basal cell carcinoma of the eyelid treated?
Treatment options for BCC consist of surgery, vismodegib, radiotherapy and imiquimod. Surgical excision using Mohs micrographic surgery or wide surgical excision with frozen section margin control is the first consideration for treatment of periocular BCC.
How do I know when to stop using fluorouracil?
Erythema develops in several days. After continued application, the damaged skin becomes painful and inflamed with a beefy-red appearance with erosions and crusting. At this point, the medication should be stopped.
How effective is fluorouracil?
Topical 5-fluorouracil (5-FU) for the treatment of widespread multiple AK lesions has cure rates of more than 90 percent. The associated skin irritation, however, may lead patients to prematurely discontinue treatment.
What does basal cell carcinoma of the eyelid look like?
Patients with basal cell carcinomas most commonly notice a reddish nodule slowly forming on their eyelid. The tumor is most commonly found on the lower eyelid, followed by the medial canthus (skin toward the nose) and can occur on the upper eyelid.
How do you get rid of basal cell carcinoma without surgery?
Cryotherapy. Cryotherapy is a nonsurgical treatment for basal cell carcinoma. Your doctor applies liquid nitrogen to the tumor, freezing the abnormal tissue.