Is 5-FU a vesicant?
However, 5-FU is typically given as an injection into the vein, as a slow IV push, or as an infusion. It is considered an irritant, not a vesicant.
What is a 5-FU injection?
FLUOROURACIL, 5-FU (flure oh YOOR a sil) is a chemotherapy drug. It slows the growth of cancer cells. This medicine is used to treat many types of cancer like breast cancer, colon or rectal cancer, pancreatic cancer, and stomach cancer.
Is cytarabine a vesicant or irritant?
Chemotherapy vesicant & irritant properties and suggested management for extravasation
Drug | Vesicant or Irritant |
---|---|
Cytarabine liposomal (DepoCyt) | Irritant |
Dacarbazine (DTIC) | Irritant |
Dactinomycin (Cosmegen) | Vesicant |
Daunorubicin (Cerubidine) | Vesicant |
Is docetaxel a vesicant?
Although docetaxel does appear to be a vesicant, it should be noted that the reaction following docetaxel extravasation where no blistering occurred has been falsely mislabeled as a vesicant-type reaction [Ho et al. 2003].
How long can you stay on 5FU?
If you are using fluorouracil to treat basal cell carcinoma, you should continue using it until the lesions are gone. This usually takes at least 3 to 6 weeks, but may take as long as 10 to 12 weeks.
What does 5FU mean?
Fluorouracil is also known as FU or 5FU and is one of the most commonly used drugs to treat cancer. It is most often used in combination with other cancer drugs to treat many types of cancer including: breast cancer. head and neck cancers.
What drugs are vesicants?
Vesicants: Drugs that can result in tissue necrosis or formation of blisters when accidentally infused into tissue surrounding a vein[14]. They include Actinomycin D, Dactinomycin, Daunorubicin, Doxorubicin, Epirubicin, Idarubicin, Mitomycin C, Vinblastine, Vindesine, Vincristine, and Vinorelbine.
Why should vesicants be given first?
If more drugs must be administered, vesicants should be administered first because veins will not have been irritated by other agents and because post-vesicant flushing will preserve venous integrity (BIII).
What is infiltration in chemotherapy?
Infiltration is the inadvertent administration of a nonvesicant or irritant solution or medication into the surrounding tissues. 1,2. Nonvesicants are agents that rarely produce acute reactions or destroy the tissue when they infiltrate.