What is penicillin G used for in pregnancy?
The intramuscular injection of benzathine penicillin G 2.4 million units weekly for 3 consecutive weeks to syphilitic pregnant women was again confirmed to be clinically effective for prevention of their neonates from congenital syphilis and well accepted as treatment for syphilis in pregnancy.
How is benzathine administered?
Penicillin G benzathine must be injected slowly and deeply into a muscle of the buttock or hip. Do not inject this medicine near or into an artery, vein, or nerve. Dangerous or fatal side effects could occur.
What are the side effects of benzathine penicillin?
Common side effects may include:
- nausea, vomiting, diarrhea;
- itching, sweating, allergic reaction;
- flushing (sudden warmth, redness, or tingly feeling);
- feeling anxious or nervous;
- headache, dizziness, drowsiness; or.
- pain, swelling, or bruising where an injection was given.
Is benzathine penicillin safe in early pregnancy?
One injection of 2.4 million units of intramuscular benzathine penicillin is recommended for pregnant women with early stage syphilis and three injections spaced by one week apart are recommended for late or unknown stage syphilis .
Is benzathine penicillin safe?
Conclusion: Studies that assessed the risk of serious adverse events due to benzathine penicillin treatment in pregnant women were scarce, but no reports of adverse reactions were found. The incidence of severe adverse outcomes was very low in the general population.
How long does penicillin G benzathine stay in your system?
Due to the slow absorption and the hydrolysis, the concentration of the drug in the blood remain lower but for a prolonged period of time. After a 1.2 million unit injection, adults have detectable drug concentrations for 14 days, often longer. The medication is excreted by renal tubular excretion.
Why is benzathine penicillin not given IV?
Penicillin G benzathine and penicillin G procaine injection should never be given intravenously (into a vein), because this may cause serious or life-threatening side effects or death.
How long does benzathine stay in the body?
Can benzathine penicillin cure?
A single intramuscular injection of long acting Benzathine penicillin G (2.4 million units administered intramuscularly) will cure a person who has primary, secondary or early latent syphilis.
What is benzathine penicillin used for?
What is penicillin G benzathine and penicillin G procaine? Penicillin G benzathine and penicillin G procaine is a combination slow-onset antibiotic that is used to treat many types of severe infections caused by bacteria, including strep infections, pneumonia, and scarlet fever.
Is benzathine penicillin painful?
Intramuscular (IM) Penicillin G Benzathine (PGB) is the cornerstone of the treatment of primary syphilis , but its administration is associated with sharp pain at the site of the injection that sometimes may be of severe intensity.
What kind of injection is Bicillin G benzathine?
Bicillin L-A (penicillin G benzathine injectable suspension) is available for deep intramuscular injection. Penicillin G benzathine is prepared by the reaction of dibenzylethylene diamine with two molecules of penicillin G. It is chemically designated as (2S, 5R, 6R )-3,3-Dimethyl-7-oxo-6-
Are there any side effects from penicillin G benzathine injection?
Penicillin G benzathine injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment: Penicillin G benzathine injection may cause other side effects.
Where does penicillin G benzathine injection take place?
Penicillin G benzathine injection comes as a suspension (liquid) in a prefilled syringe to inject into the muscles of the buttocks or thigh by a doctor or nurse in a medical facility. Penicillin G benzathine injection may be given as a single dose.
How is penicillin G benzathine used to treat colds?
Penicillin G benzathine injection is used to treat and prevent certain infections caused by bacteria. Penicillin G benzathine injection is in a class of antibiotics called penicillins. It works by killing bacteria that cause infections. Antibiotics such as penicillin G benzathine injection will not work for colds,…