How do you say denosumab injection?

Denosumab (pronounced den-oh-sue-mab) is a type of targeted therapy called a monoclonal antibody.

What is the drug denosumab used for?

Denosumab injection (Xgeva) is used Denosumab injection is in a class of medications called RANK ligand inhibitors. It works to prevent bone loss by blocking a certain receptor in the body to decrease bone breakdown. It works to treat GCTB by blocking a certain receptor in the tumor cells which slows the tumor growth.

How do you say xgeva?

Pronunciation: (ex-JEE-vuh)

What is the monoclonal antibody used for the treatment of osteoporosis?

Denosumab is the only monoclonal antibody approved by the FDA as a therapy for osteoporosis. Clinical studies indicate that the treatment of osteoporotic patients with denosumab for a 10-year period leads to a continuous increase in bone mineral density (BMD) with a low incidence of adverse effects.

Does denosumab cause hair loss?

Hair loss. During initial clinical trials of Prolia, hair loss wasn’t reported as a side effect. However, hair loss was reported in postmarketing studies of the drug. (Postmarketing studies are done after a drug is approved and has been released on the market.)

Is denosumab safe to take?

In clinical trials of women with osteoporosis and low bone mineral density, denosumab has been well tolerated, with overall rates of adverse events and serious adverse events in women treated with denosumab similar to those receiving placebo.

Is hormone replacement therapy the solution for osteoporosis?

Hormone replacement therapy (HRT) — either estrogen alone or a combination of estrogen and progestin — is approved for the prevention and treatment of osteoporosis in women.

Is denosumab safe?

Is denosumab expensive?

Subcutaneous denosumab costs $1,828 per dose and $78 for administration. Base-case results showed mean costs of monthly denosumab treatments ($57,200) appeared more than nine times higher than zoledronic acid every 3 months ($5,667) or every month ($9,290).