Is junctional melanocytic nevus cancer?
A junctional nevus is a non-cancerous type of growth made up of melanocytes. Junctional nevi are usually seen in individuals of lighter skin complexion and can be found anywhere on the body.
What is junctional activity in melanoma?
Besides, the most important diagnostic criterion is the junctional activity of the tumor on histopathologic examination (junctional activity defined as intraepithelial dissemination involves the presence of pigmented dendritic cells at the junction of the epithelium and lamina propria).
What is a junctional melanocytic proliferation?
The histological term, junctional melanocytic hyperplasia (JMH), refers to the proliferation of single melanocytes along the dermal epidermal junction that is the basal layer where normal melanocytes reside. JMH is characteristic of lentigo simplex, junctional nevus, and dysplastic nevus.
How do I get rid of junctional nevus?
Is Removal Possible? Small nevi can be removed by simple surgical excision. The nevus is cut out, and the adjacent skin stitched together leaving a small scar. Removal of a large congenital nevus, however, requires replacement of the affected skin.
Can junctional nevus be removed?
Therefore, most moles will never need to be treated. However, suspicion that a mole may be a melanoma, chronic irritation, cosmetic concerns, or a change in the size, shape, or pigmentation of the mole are reasons that a junctional nevus to be removed via excisional biopsy.
Is atypical junctional melanocytic proliferation melanoma?
Atypical junctional melanocytic hyperplasia (AJMH) is a poorly defined clinical entity. For most dermatologists, it represents a melanocytic proliferation that insufficient for a definitive diagnosis of melanoma in situ.
What does the pattern of junctional nevi look like?
The junctional nevus is composed of discrete nests of melanocytes/nevus cells at the dermoepidermal junction, usually located on the rete ridges, which often show some accentuation. The cells are oval to cuboidal in shape, with clear cytoplasm containing a variable amount of melanin pigment. Mitoses are rare or absent.
How big does a dysplastic junctional nevi get?
Dysplastic (Atypical) Nevus. Junctional nevi will typically grow to be 3 or 4 mm across, stop growing sideways, and begin to evolve into a compound nevus. This evolution continues through the compound nevus stage to the dermal nevus stage. In the dermal nevus all of the melanocytes are in the dermis.
What did the doctor say about junctional melanocytic nevus?
The doctor basically said, it is an atypical mole and cells that are changing and we’re lucky to have caught it now. Im feeling so relieved but still need some clarity. This has been the worst week of my life thus far waiting for the report since I have a 8 week and 18 month old.
What kind of melanoma is dysplastic nevus associated with?
DDx Dysplastic nevus, abbreviated DN, is a common melanocytic lesion that is closely associated with malignant melanoma . It is also known as atypical nevus, dysplastic melanocytic nevus, Clark nevus, and nevus with architectural disorder .
What is the prognosis of a dysplastic melanocytic nevi?
Prognosis. Dysplastic (atypical, Clark) melanocytic nevi occur in the setting of sporadic and familial melanomas and are an important risk factor in development of cutaneous melanoma. Increased numbers of clinically dysplastic (atypical, Clark) melanocytic nevi are associated with a greater risk for melanoma.